이론화학, 양자화학, 컴퓨터를 이용한 신물질 및 신약개발, 분자구조와 반응성에
대한 연구.
(1) 한국과학기술평가원 : 인체질환을 영상진단하기 위한 표지화 기술 (국가지정연구실)
(2) 학술진흥재단 : 순수기초그룹 : 유기반응의 구조.반응성에 대한 실험 및 이론적 연구
(3) 교육부, 학술진흥재단 : BK21 기초과학분야 사업 (분자구조 및 반응동력학 연구사업팀)
(4) 프런디어 21 연구과제 : 단백질 구조분석을 통한 트랜스아미나제 효소 특성 규명
및 이를 이용한 의약용 비천연아미노산 생산기술의 개발
이본수 교수 주요 연구 업적
<1996년도>
1. B-S. Lee, C. K. Lee, J. W. Choi, and I. Lee, "Ab Initio Studies on the Hetero Diels-Alder Cycloaddition," Bull. Korean Chem. Soc., 17, 849 (1996). (I.F. = 0.412)
2. I. Lee, D. Lee, J. K. Lee, C. K. Kim, and B-S. Lee, "Theoretical studies on the base-catalysed rearrangement of 4,4'-disubstituted benzils in the gas phase and aqueous solution," J. Chem. Soc. Perkin Trans 2, 2519 (1996). (I.F. = 1.845)
3. H. J. Koh, T. H. Kim. B-S. Lee, and I. Lee, "Kinetics
of Aminolysis of Phenyl Phenoxyacetates with Benzylamines in Acetonitrile,"
J. Chem. Research (S),
482 (1996). (I.F. = 0.666)
<1997년도>
1. W. K. Kim, W. S. Ryu, C. K. Sohn, B-S. Lee, C. K. Kim, and I. Lee, "Theoretical Studies on the Base-Catalyzed Deprotonation of Sulfonyl-Activated Carbon Acids," Bull. Korean Chem. Soc., 18, 208 (1997). (I.F. = 0.412)
2. K. S. Kim, S. J. Cho, K. S. Oh, J. S. Son, J. Kim, J. Y. Lee, S. J. Lee, S. Lee, Y-T. Chang, S-K. Chung, T-K. Ha, B-S. Lee, and I. Lee, "Theoretical Studies of regioselectivity of myo-Inositol Derivatives : Importance of Solvent Dielect Constants," J. Phys. Chem. A. 101, 3776 (1997). (I.F. = 3.392)
3. D. Lee, C. K. Kim, B-S. Lee, and I. Lee, "A Theoretical Study on Keto-Enol Tautomerization Involving Simple Carbonyl Derivatives," J. Compt. Chem., 18, 56 (1997). (I.F. = 3.357)
4. J. K. Lee, C. K. Kim, B-S. Lee, and I. Lee, "Theoretical Studies on the Gas-Phase Nucleophlic Ring Opening of 3,4-Epimino-,3,4-Epoxy-, and 3,4-Epithio-1-Butene," J. Phys. Chem. A, 101, 2893 (1997). (I.F. = 3.392)
5. I. S. Han, C. K. Kim, C. K. Kim, B-S. Lee, and I. Lee, "Ab initio Studies of Three-Membered Ring Formation through Intramolecular Nucleophilic Substitution," J. Comput. Chem., 18, 1773 (1997). (I.F. = 3.357)
6. D. S. Chung, C. K. Kim, B-S. Lee, and I. Lee, "Theoretical Studies of Competitive Gas-Phase SN2 and E2 Reactions of NCCH2CH2Cl with OH- and SH-," J. Phys. Chem. A, 101, 9097 (1997). (I.F. = 3.392)
7. I. Lee, C. K. Kim, B-S. Lee, C. K. Kim, H. W. Lee, and I. S. Han, "Theoretical Studies on the Transition-State Imbalance in Malononitrile Anion-Forming Reactions in the Gas Phase and in Water," J. Phys. Org. Chem., 10, 908 (1997). (I.F. = 1.118)
<1998년도>
1. C. K. Kim, I. Y. Lee, D. S. Chung, B-S. Lee, and I.
Lee, "PM3 studies on the Acid Catalyzed Hydrolysis of 1-Phenoxyethyl Propiorate,"
Bull. Korean. Chem. Soc.
19, 993 (1998).
(I.F. = 0.412)
<1999년도>
1. I. Lee, H. Y. Park, I. S. Han, C. K. Kim, C. K. Kim,
and B-S. Lee, "Theoretical Studies on the Gas-Phase Alkylation of Delocalized
Ambident Anions with Methyl Fluoride," Bull.
Korean Chem. Soc.,
20(5), 559 (1999).
(I.F. = 0.412)
2. Young Sook Park, Ikchoon Lee, and Bon-Su Lee, "Density functional theory studies of hetero-Diels-Alder reactions" New J. Chem., 23, 707 (1999). (I.F. = 1.851)
<2000년도>
1. Hyung Yeon Park, Chan Kyung Kim, Hai Whang Lee, Ikchoon Lee and Bon-Su Lee,
"Theoretical Studies on Gas-Phase Reactions of Negative lons with Alkyl
Nitrites", Bull. Korean Chem. Soc, 21(8)
823 (2000) (I.F. = 0.412)
2. Ikchoon Lee, Chang Kon Kim, Hong Guang Li, Hai Whang Lee, and Bon-Su Lee,
"Inversion of stationary point levels in a flat transition structure region
on account of vibrational energy, " Chem Phy. Letter, 320, 307 (2000) (I.F. = 2.269)
<2001년도>
1. Ikchoon Lee, Chang Kon Kim, Hong Guang Li, Chan Kyung Kim, Soon Ki Rhee and Bon-Su Lee. "Nucleophilic Substitution at the Imidoyl Carbon Atom : Intermediate Machanistic and Reactivity Behavior between Carbonyl and Vinyl Carbon Substitution." J. Am. Chem. Soc. 123, 2326-2333, (2001) (I.F = 6.025)
2. Wang Ki Kim, Yong Bin Kim, Chang Kon Kim and Bon-Su Lee. "Theoretical Studies on the Protonation Equilibria of Benzoyl Derivatives." Bull. Korean Chem Soc., 22(4), 395-400 (2001) (I.F. = 0.412)
3. Chang Kon Kim, Dong Soo Chung, Chang Kyung Kim, Bon-Su Lee, Yeong-Jin Chung, Byung Choon Lee, Ikchoon Lee and Bon-Su Lee . "Theoretical Studies on the Competitive SN2 Reactions of O-Imiidomethyl Derivatives of Phenols with OH-. " Bull. Korean Chem Soc., 22(1), 25-29. (2001) (I.F. = 0.412)
4. Kim Chang Kon, Kim Chan Kyung, Lee Bon-Su, Won Jongok, Kim Hoon Sik, Kang Yong Soo. "Density Functional Theory Studies on the Reaction Mechanisms of Silver Ions with Ethylene in Facilitated Transport Membranes: A Modeling Study." J. Phy. Chem. A 105, 9024-9028, (2001) (I.F = 2.754)
5. Sung Wan Hong, Han Joong Koh, Yong Lee, Bon-Su Lee, Hai Whang Lee and Ikchoon Lee. "Structure-Reactivity Relationships in the Pyridinolysis of N-methyl-N-arylcarbamoyl Chlorides in Dimethyl Sulfoxide." J. Org. Chem. 66, 8549-8555, (2001) (I.F = 3.689)
<2002년도>
1. Lee Byoung Se, Chu Soyoung, Bon-Su Lee, Chi Dae Yoon, Song Yun Seon, Jin Chang Bae. "Syntheses and Binding affinities of 6-Nitroquipazine Analogues for serotonin transporter." Bioorg. & Med. Chem. Lett. 12, 811-815, (2002) (I.F = 1.759)
2. Chang Kon Kim, Hong Guang Li, Bon-Su Lee, Chan Kyung Kim, Hai Whang Lee and Ikchoon Lee. "Gas-Phase Identity Nucleophilic Substitution Reactions of Cyclopropenyl Halides." J. Org. Chem. 67, 1953-1960, (2002) (I.F = 3.689)
3. Roh Eun Joo, Kim Deukjoon, Choi Jun Yong, Bon-Su Lee, Lee Chong Ock, Song Choong Eui. "Synthesis, biological activity and receptor-based 3-D QSAR study of 3'-N-substituted-3'-N-debenzoylpaclitaxel analogues." Bioorg. & Med. Chem. Lett. 10, 3135-3143, (2002) (I.F = 1.759)
4. Jin Hee Lee, Chan Kyung Kim, Bon-Su Lee, Hai Whang Lee and Ikchoon Lee. "Theoretical studies on hetero Diels-Alder Reactions of Sulfur Diimides." New J. Chem. 26, 1693-1697, (2002) (I.F = 2.206)
<2003년도>
1. K. S. Lee, K. K. Adhikary, Hai Whang Lee, Bon-Su Lee and Ikchoon Lee. "Nucleophilic Substitution Reactions of α-Chloroacetanilides with Benzylamines in Dimethyl Sulfoxide." Org. Biomol. Chem. 1, 1989∼1994 (2003)
2. Hong Guang Li, Chan Kon Kim, Bon-Su Lee, Chang Kyung Kim, Hai Whang Lee and Ikchoon Lee. "Theoretical Studies of the Gas-Phase Identity Nucleophilic Substitution Reactions of Cyclopentadienyl Halides." Bull. Korean, Chem. Soc., 24, 583~592 (2003) (I.F = 0.419)
3. Yongsok Seo, Seong Uk Hong, Bon-Su Lee, Overcoming the “Upper Bound” in Polymeric Gas-Separation Membranes. Angew. Chem. Int. Ed. 42, 1145~1149 (2003)
4. Byoung Se Lee, Soyoung Chu, Kyo Chul Lee,이본수, Dae Yoon Chi, Yearn Seong Choe,Sang Eun Kim, Yun Seon Song, Changbae Jin, Syntheses and Binding Affinities of 6-Nitroquipazine Analogues for Serotonin Transporter: Part 3.y A Potential 5-HT Transporter Imaging Agent, 3-(3-[18F]Fluoropropyl)-6-nitroquipazine. Bioorg. Med. Chem. 11, 4949-4958 (2003)